Fast dissolving tablet
1 Student Shraddha Institute of Pharmacy, Kondala Zambre, Washim 444505, India.
2 Department of Industrial Pharmacy Shraddha Institute of Pharmacy, Washim, India.
3 Department of Pharmacology, Shraddha Institute of Pharmacy, Kondala Zambre, Washim, India.
Review Article
GSC Biological and Pharmaceutical Sciences, 2024, 27(01), 001–007.
Article DOI: 10.30574/gscbps.2024.27.1.0096
Publication history:
Received on 09 February 2024; revised on 23 March 2024; accepted on 26 March 2024
Abstract:
Fast dissolving tablets have emerged as a popular dosage form, particularly beneficial for pediatric and geriatric patients facing challenges such as dysphagia or hand tremors. These tablets dissolve quickly in saliva without needing water, enhancing compliance and effectiveness of therapy. They offer advantages like easy portability, accurate dosing, and improved bioavailability. Various technologies, including spray drying and melt granulation, have been developed for their manufacturing. This review provides comprehensive information on fast dissolving tablets, covering their definition, advantages, limitations, challenges, and available formulations. The design of an oral drug delivery system prioritizes convenience in administration and improved patient compliance, making it the preferred route of drug delivery despite certain drawbacks. Over the last decade, there has been a growing demand for Fast Disintegrating Tablets (FDTS), turning this field into a rapidly expanding area within the pharmaceutical industry. The formulation’s popularity and effectiveness have led to the development of various FDT technologies. These technologies aim to achieve rapid tablet disintegration and mouth dissolution within five seconds, eliminating the need for chewing or water intake. This characteristic is particularly advantageous for populations such as pediatrics, geriatrics, and patients facing difficulties in swallowing conventional tablets and capsules. The formulation of an easily administrable dosage form, considering challenges like swallowing difficulties and low patient compliance, has driven the creation of orally disintegrating tablets. Traditional preparation methods include spray drying, freeze drying, direct compression, molding, and sublimation. In addition, new technologies have been devised to enhance the production of orodispersible tablets.
Keywords:
Fast dissolving tablets; FDTS; Superdisintegrants; Mouth dissolving tablets; Fast melting
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
