GC-MS analysis, pharmaceutical and industrial significance of phytochemicals present in Annona muricata from Eziobodo, Imo State, Nigeria
1 Department of Biochemistry, School of Biological Sciences, Federal University of Technology Owerri, Nigeria.
2 Department of Applied Biochemistry, Faculty of Biosciences, Nnamdi Azikiwe University Awka, Nigeria.
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 27(01), 174–180.
Article DOI: 10.30574/gscbps.2024.27.1.0130
Publication history:
Received on 03 March 2024; revised on 15 April 2024; accepted on 18 April 2024
Abstract:
Background: The conduct of screenings for therapeutic alternatives derived from medicinal plants has emerged as a useful tool for drug discovery and valuable information for further phytotherapeutic studies.
Objective: To carry out chemical characterization of ethanol leaf extract of Annona muricata using gas chromatography mass spectroscopy (GC-MS).
Materials and method: Apparently healthy leaf samples were taxonomically identified, air-dried and subjected to maceration to obtain ethanol extract stock. GC-MS analysis was utilized to investigate phytochemical composition.
Results: The GC-MS analysis spectra was characterized by a total of twenty-six constituents at different retention times which were all identified. Dominant components present included n-Hexadecanoic acid, Oleic Acid and γ-Sitosterol with peak areas 32.60%, 24.35% and 9.10% respectively. Additional constituents were Dodecanoic acid (peak area 4.31%), 13 Octadecenal, (Z) (peak area 2.83%), Bis (2-ethylhexyl) phthalate (peak area 2.31%), Tetradecanoic acid (peak area 2.34%), Trapidil (peak area 2.10%) while others occupied less than 2% peak area.
Conclusion: This study suggests that the ethanol leaf extract of A. muricata could possess vital compounds of pharmaceutical and industrial relevance.
Keywords:
GCMS; Annona muricata; Ethanol extract; Phytochemicals
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